Plasmapheresis
Haematology / Nephrology · Transfusion Medicine
2–4 hours per session
Duration
Outpatient
Setting
Same-day procedure; courses of 5–7 exchanges over 2 weeks typically
Recovery
₹10,000+
Cost
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📖About Plasmapheresis
Therapeutic plasma exchange to remove pathological antibodies or proteins from the circulation.
Duration
2–4 hours per session
Setting
Outpatient
Recovery
Same-day procedure; courses of 5–7 exchanges over 2 weeks typically
Cost Range
₹10,000 – ₹30,000 per session
Specialty
Haematology / Nephrology
Success Rate
60–90% response (disease specific)
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📋Indications — Who Needs This Treatment?
- 1Guillain-Barré, myasthenia gravis, TTP, anti-GBM disease, ANCA vasculitis, hyperviscosity syndrome
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🔬How the Treatment is Performed
- 1Large-bore central or peripheral access
- 2centrifugation or membrane filtration separates and removes plasma
- 3replacement with albumin or FFP.
📝Pre-Treatment Preparation
- 1Consult a Haematology / Nephrology specialist to confirm suitability for Plasmapheresis
- 2Complete all pre-treatment investigations as directed — blood tests, imaging, ECG, or specialist clearance
- 3Disclose all current medications, supplements, and allergies to your treating physician
- 4Fast (nil by mouth) for 6–8 hours if the treatment involves anaesthesia or sedation
- 5Arrange for a responsible adult to accompany you, especially for procedures requiring sedation
- 6Follow all specific pre-treatment instructions issued by your care team regarding diet or medication changes
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⚠️Possible Side Effects & Risks
- 1Hypocalcaemia, hypotension, bleeding, infection, allergic reactions to replacement fluid
🩹Recovery & Aftercare
- 1Same-day procedure
- 2courses of 5–7 exchanges over 2 weeks typically
Treatment Journey — What to Expect
Before Treatment
Pre-treatment workup, consent signing, and preparation as instructed by your care team. Baseline tests and imaging completed.
During Treatment
Plasmapheresis is administered over 2–4 hours per session. Vital signs monitored. Your specialist manages any immediate side effects.
Immediate Post-Treatment
Recovery observation, assessment of initial response, discharge instructions provided. Follow-up appointment scheduled.
Long-term Recovery (Same-day procedure; courses of 5–7 exchanges over 2 weeks typically)
Return to normal activities as tolerated. Monitoring for treatment response and side effects. Ongoing support from your specialist.
Plasmapheresis Cost in India (2024–25)
| Component | Govt / Budget | Private |
|---|---|---|
| Specialist Consultation | ₹300 – ₹800 | ₹1,000 – ₹3,000 |
| Procedure / Session Cost | ₹2,000 – ₹10,000 | ₹10,000 – ₹50,000 |
| Medications | ₹500 – ₹3,000 | ₹2,000 – ₹15,000 |
| Follow-up & Monitoring | ₹300 – ₹1,000 | ₹1,000 – ₹5,000 |
| Rehabilitation / Aftercare | ₹1,000 – ₹5,000 | ₹5,000 – ₹25,000 |
* Estimates for India 2024–25. CGHS / Ayushman Bharat may cover eligible treatments. Individual costs vary by hospital, city, and complexity.
Treatment Outcomes
Plasmapheresis has a documented success rate of 60–90% response (disease specific) when performed by qualified specialists at accredited facilities. Individual outcomes vary based on disease stage, patient health, and adherence to the treatment plan and aftercare instructions.
Frequently Asked Questions
What is Plasmapheresis?+
Therapeutic plasma exchange to remove pathological antibodies or proteins from the circulation.
Who is a candidate for Plasmapheresis?+
Plasmapheresis is recommended for patients diagnosed with specific conditions where other approaches have been insufficient. Your Haematology / Nephrology specialist will assess your suitability based on your diagnosis, health history, and treatment goals.
How long does Plasmapheresis take?+
The typical duration is 2–4 hours per session. This may vary based on the complexity of your case and individual response to treatment.
What is the recovery time after Plasmapheresis?+
Recovery typically takes Same-day procedure; courses of 5–7 exchanges over 2 weeks typically. Your care team will provide specific instructions based on your response and overall health.
What are the risks or side effects of Plasmapheresis?+
Side effects vary by individual and are detailed in the section above. Your specialist will discuss all risks and benefits with you before treatment begins. Serious adverse effects are uncommon but are part of the informed consent process.
What is the success rate of Plasmapheresis?+
Plasmapheresis has a documented success rate of 60–90% response (disease specific) at accredited facilities. Outcomes depend on disease stage, patient health, and adherence to the treatment plan and aftercare instructions.
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⚕️ Medical Disclaimer
This page is for informational purposes only. Always consult a qualified specialist before deciding on any treatment. In emergencies, call 112.
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