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All Vaccines/Malaria Vaccine (R21/Matrix-M)
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Travel5–36 months (children in endemic areas)75–80% efficacy in seasonal malaria prevention Efficacy

Malaria Vaccine (R21/Matrix-M)

Travel Vaccine · 5–36 months (children in endemic areas)

5–36 months (children in endemic areas)

Age Group

75–80% efficacy in seasonal malaria prevention

Efficacy

Pricing being established for endemic countries

Cost Range

Serum Institute of India (R21/Matrix-M)

Manufacturer

💉About the Malaria Vaccine (R21/Matrix-M) Vaccine

R21/Matrix-M is a malaria vaccine developed by the University of Oxford and Serum Institute of India. WHO recommended RTS,S in 2021; R21 shows higher efficacy. First vaccine to significantly reduce malaria in children.

Efficacy

75–80% efficacy in seasonal malaria prevention

Age Group

5–36 months (children in endemic areas)

Cost Range

Pricing being established for endemic countries

Manufacturer

Serum Institute of India (R21/Matrix-M)

Category

Travel

Protection

1 disease

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Book your Malaria Vaccine (R21/Matrix-M) at 200+ certified hospitals and clinics across India. Walk-in or scheduled appointments available.

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🛡️Diseases Prevented

Plasmodium falciparum malaria

📅Dosage Schedule

4 doses: 3 primary doses monthly, then booster at 18 months. Seasonal malaria vaccination: 3 doses before malaria season annually.

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⚠️Common Side Effects

  • 1Injection site pain
  • 2fever
  • 3irritability
  • 4drowsiness.

🚫Who Should NOT Get This Vaccine

  • 1Hypersensitivity to vaccine components. Not yet recommended for non-endemic travelers.

Who Should Get the Malaria Vaccine (R21/Matrix-M) Vaccine

  • 15–36 months (children in endemic areas) — as recommended by national immunisation guidelines
  • 2Individuals without prior immunity or with incomplete vaccination history
  • 3People at higher risk of exposure due to travel, occupation, or close contact with infected individuals
  • 4Those advised by a healthcare provider based on their specific health profile and risk factors
  • 5Pregnant women, elderly, and immunocompromised individuals should consult their doctor for personalised advice
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Your Vaccination Journey

  1. Before Vaccination

    Consult your doctor to confirm eligibility for the Malaria Vaccine (R21/Matrix-M). Discuss any allergies, current medications, and your medical history. Avoid getting vaccinated if you have a fever or acute illness.

  2. Vaccination Day

    The Malaria Vaccine (R21/Matrix-M) is administered by injection or orally by a certified healthcare professional. The procedure takes just a few minutes. You will be observed for 15–30 minutes for immediate reactions.

  3. 24–48 Hours After

    Mild side effects such as soreness at the injection site, low-grade fever, or fatigue are normal and resolve on their own. Stay hydrated and rest. Seek medical attention if symptoms are severe.

  4. Follow-Up Doses

    Complete the full dosage schedule as prescribed — skipping doses reduces effectiveness. Follow-up doses are usually given within weeks to months of the first dose.

Malaria Vaccine (R21/Matrix-M) Vaccination Cost in India (2024–25)

ServiceGovt / FreePrivate
Vaccine CostFree (UIP eligible)Pricing being established for endemic countries
Administration FeeNil₹100 – ₹500
Pre-vaccination Consultation₹0 – ₹100₹500 – ₹1,500
Home Vaccination ServiceNot available₹300 – ₹800 extra
Digital CertificateFree (Co-WIN)Included / ₹50–₹200

* Costs are approximate estimates for India (2024–25). Prices vary by city and provider. Under India's Universal Immunisation Programme (UIP), several vaccines are available free at government health centres.

Frequently Asked Questions

What is the Malaria Vaccine (R21/Matrix-M) vaccine?+

R21/Matrix-M is a malaria vaccine developed by the University of Oxford and Serum Institute of India. WHO recommended RTS,S in 2021; R21 shows higher efficacy. First vaccine to significantly reduce malaria in children.

Who should get the Malaria Vaccine (R21/Matrix-M) vaccine?+

The Malaria Vaccine (R21/Matrix-M) is recommended for 5–36 months (children in endemic areas). It falls under the Travel vaccine category. Consult your doctor to confirm if this vaccine is right for you based on your health history and existing immunity.

How effective is the Malaria Vaccine (R21/Matrix-M) vaccine?+

The Malaria Vaccine (R21/Matrix-M) has an efficacy of 75–80% efficacy in seasonal malaria prevention. This means it provides significant protection against Plasmodium falciparum malaria. Efficacy may vary based on age, health status, and the specific strain encountered.

What are the common side effects of Malaria Vaccine (R21/Matrix-M)?+

Common side effects include: Injection site pain; fever; irritability; drowsiness.. These are typically mild and resolve within 1–3 days. Serious allergic reactions are rare — if you experience difficulty breathing, hives, or rapid heartbeat after vaccination, seek emergency care immediately.

Who should NOT get the Malaria Vaccine (R21/Matrix-M) vaccine?+

The Malaria Vaccine (R21/Matrix-M) should be avoided by: Hypersensitivity to vaccine components. Not yet recommended for non-endemic travelers.. Always inform your healthcare provider of your full medical history before vaccination.

How much does the Malaria Vaccine (R21/Matrix-M) vaccine cost in India?+

The Malaria Vaccine (R21/Matrix-M) typically costs Pricing being established for endemic countries in India. Government health centres may offer it free or at subsidised prices for eligible age groups. Private hospitals and clinics may charge differently. Additional fees may apply for administration.

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  • WHO-recognised vaccination centres
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Book Your Vaccination

Find certified travel vaccine centres

Quick Cost Estimate

Govt / FreeFree – ₹500
Private ClinicPricing being established for endemic countries
Home Service+ ₹300 – ₹800
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Malaria Vaccine (R21/Matrix-M) Available Now

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⚕️ Medical Disclaimer

This page is for informational purposes only and does not substitute professional medical advice. Always consult a qualified healthcare professional before vaccination. In emergencies, call 112.