CA-125 (Ovarian Cancer Marker) Test

Is CA-125 a reliable screening test for all women?

No — it's not recommended as a standalone screening test for the general population, since many benign conditions can also raise CA-125, leading to false alarms. It's most valuable in women with a known pelvic mass or diagnosed ovarian cancer.

Can CA-125 be elevated without cancer?

Yes, conditions like endometriosis, fibroids, pelvic infections, and even normal menstruation can all raise CA-125 to varying degrees, which is why it's interpreted alongside imaging and clinical findings.

How is CA-125 used during cancer treatment?

It's tracked over time as part of monitoring treatment response — a declining trend generally suggests treatment is working, while a rising trend may prompt further investigation for recurrence.