Anti-TPO (Anti-Thyroid Peroxidase) Antibody Test

Does a positive Anti-TPO result mean I have thyroid disease?

Not automatically — some healthy people test positive without ever developing thyroid dysfunction. Your doctor will interpret it alongside your TSH, T4 levels, and symptoms, and may recommend periodic monitoring.

Can Anti-TPO antibodies go away?

Antibody levels can fluctuate over time and sometimes decrease, but they often persist for years once present. Levels are generally used to support a diagnosis rather than tracked closely as a treatment goal.

Is this test relevant during pregnancy?

Yes, thyroid autoimmunity has been linked to fertility difficulties and pregnancy complications, so some doctors screen for Anti-TPO antibodies in women trying to conceive or with a history of pregnancy loss.