Premature Ovarian Insufficiency

📖What is Premature Ovarian Insufficiency?

Premature ovarian insufficiency is a condition in which the ovaries stop functioning normally before the age of 40, leading to reduced production of estrogen and irregular or absent ovulation well before the typical age of natural menopause. Unlike menopause, ovarian function in premature ovarian insufficiency can be intermittent, with occasional ovulation and even spontaneous pregnancy still possible in a small percentage of cases, distinguishing it from complete ovarian failure. It significantly affects fertility and, due to prolonged estrogen deficiency at a young age, increases long-term risks of osteoporosis and cardiovascular disease if untreated.

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