Polycystic Kidney Disease

🔬Causes & Risk Factors

• 1Caused by inherited genetic mutations affecting proteins involved in normal kidney tubule development
• 2most commonly following an autosomal dominant inheritance pattern in which a child of an affected parent has a fifty percent chance of inheriting the condition. A less common
• 3more severe form follows a different inheritance pattern and typically presents in infancy. The specific genetic mutation influences the rate of disease progression and the age at which kidney failure may eventually develop.