Hirschsprung Disease

📖What is Hirschsprung Disease?

Hirschsprung disease is a congenital condition in which nerve cells that normally control the muscle contractions needed to move stool through the intestine are missing from the end portion of the large intestine, causing that segment to remain persistently tight and unable to relax. This leads to a functional blockage, as stool cannot pass normally through the affected segment, causing it to back up and the bowel above it to become distended. It typically becomes apparent in the newborn period, most notably through a failure to pass the first stool within the expected timeframe after birth, and requires surgical treatment.

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