Sickle Cell Disease Specialists in Vasant Vihar1, Delhi

What is Sickle Cell Disease?

Sickle Cell Disease is an inherited blood disorder in which red blood cells become rigid and crescent-shaped due to an abnormal form of hemoglobin, causing them to break down prematurely and block blood flow through small vessels. This can lead to episodes of severe pain, called sickle cell crises, along with chronic anaemia and progressive organ damage over time. It is caused by inheriting two copies of the sickle hemoglobin gene, one from each parent. The condition requires lifelong monitoring and management to prevent and treat complications.

Causes of Sickle Cell Disease

Caused by an inherited mutation in the gene responsible for hemoglobin production, resulting in abnormal hemoglobin S that distorts red blood cells into a sickle shape under low oxygen conditions. The condition occurs when a person inherits the sickle cell gene from both parents, while carrying only one copy results in the milder sickle cell trait.

Symptoms of Sickle Cell Disease

Episodes of severe pain in bones, chest, and abdomen, chronic fatigue from anaemia, swelling in hands and feet, frequent infections, delayed growth in children, yellowing of skin and eyes, vision problems, shortness of breath, priapism in males

Treatment & Types of Sickle Cell Disease in Vasant Vihar1, Delhi

Management includes pain relief medications during crises, hydroxyurea to reduce the frequency of painful episodes, and blood transfusions for severe anaemia or complications. Bone marrow transplantation offers a potential cure in select cases, while newer gene therapies are emerging; preventive antibiotics and vaccinations reduce infection risk, particularly in children.

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