Bone Metastasis Specialists in Block E, Nirman Vihar, Delhi

What is Bone Metastasis?

Bone metastasis occurs when cancer cells originating from a tumour elsewhere in the body, most commonly the breast, prostate, lung, kidney, or thyroid, travel through the bloodstream and establish secondary growths within the bone. Once cancer cells settle in the bone marrow, they disrupt the normal balance between bone-building and bone-dissolving cells, leading to either weakened, destructive lesions or abnormally dense bone formation depending on the cancer type. This process significantly weakens the affected bone, making it prone to pain, fracture, and elevated blood calcium levels. Bone metastasis is a marker of advanced cancer and is typically detected using bone scans, PET imaging, MRI, or CT scans.

Causes of Bone Metastasis

Bone metastasis develops when cancer cells break away from the original tumour, enter the bloodstream or lymphatic system, and lodge within the bone marrow, where they multiply and disrupt normal bone remodeling. Certain cancers, particularly breast, prostate, lung, kidney, and thyroid cancer, have a strong tendency to spread to bone due to specific molecular interactions between cancer cells and the bone marrow environment. The vertebrae, pelvis, ribs, and long bones are the most commonly affected sites due to their rich blood supply.

Symptoms of Bone Metastasis

persistent bone pain that often worsens at night or with activity, bone fractures occurring with minimal or no trauma, swelling over the affected bone, weakness or numbness if the spine is compressed, elevated blood calcium causing nausea, confusion, or excessive thirst, fatigue, reduced mobility

Treatment & Types of Bone Metastasis in Block E, Nirman Vihar, Delhi

Treatment aims to control pain, prevent fractures, and manage the underlying cancer, using radiation therapy to relieve localized bone pain and shrink the metastatic lesion, along with bone-strengthening medications such as bisphosphonates or denosumab to reduce the risk of fracture and complications. Systemic treatment of the primary cancer, including chemotherapy, hormone therapy, or targeted therapy, is continued to control disease progression throughout the body. Surgical stabilization with rods or plates may be needed for bones at high risk of fracture, and specialized pain management is an important part of ongoing care.

Bone metastases are classified by their effect on bone structure: osteolytic lesions, which destroy and weaken bone (typical of breast and lung cancer spread), osteoblastic lesions, which cause abnormally dense, disorganized new bone formation (typical of prostate cancer spread), and mixed lesions showing features of both patterns.

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