Hirschsprung Disease Specialists in Nirman Bhawan, Delhi
Hirschsprung disease is a congenital condition in which nerve cells that normally control the muscle contractions needed to move stool through the intestine are…
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Causes of Hirschsprung Disease
Results from a failure of specialized nerve cells to migrate fully into the developing intestine during fetal development, leaving a segment of bowel, most commonly at the end of the large intestine, without the nerve cells needed to coordinate normal muscle relaxation and stool movement. It has a notable genetic component, with a family history increasing risk, and is more common in children with certain genetic conditions such as Down syndrome. The exact combination of genetic factors involved varies between affected individuals.